Transforming Cancer Treatment
OncoNOx

OX27-NO

OX27-NO is an analog of VGX™-1027(see www.inovio.com for details). OX27-NO induces apoptosis and inhibits cell growth for various tumor cell lines and is devoid the anti-inflammatory activities of the parent compound.

OX1001 is a potent inhibitor of tumor growth in mouse models of prostate and breast cancer.

For more information, please see the following scientific papers:

Maksimovic-Ivanic et al. Mol Cancer Therapeut 2008:7;510

Mijatovic et al. Nitric Oxide 2008:19;177

Donia et al. Eur J Pharmacol 2009:615;228

Mijatovic et al. Free Radic Biol Med 2010:48;1090